oxytocin

Oxytocin

Examining how the oxytocin system impacts psychophysiological processes.

Intranasal oxytocin reduces heart rate variability during a mental arithmetic task: A randomised, double-blind, placebo-controlled cross-over study

Heart rate variability (HRV) refers to variation in the interval between successive heart beats. Low HRV is an indicator of potential autonomic nervous system dysfunction. People with chronic pain often display autonomic dysregulation, especially in …

The effect of oxytocin on autonomic flexibility following a traumatic experience: A pilot study

A traumatic experience can lead to poor emotion-regulation and hyperarousal. The hormone oxytocin appears to normalise emotional reactivity in persons with symptoms of psychopathology, and modulates the salience of social and emotional cues, leading …

Sex-specific effects of intranasal oxytocin on thermal pain perception: A randomised, double-blind, placebo-controlled cross-over study

Chronic neck and shoulder pain (CNSP) is a common musculoskeletal disorder in adults, which is linked to hypersensitivity to noxious stimuli. The hormone oxytocin has been implicated as a potential therapeutic for the management of chronic pain …

Oxytocin and the modulation of pain experience: Implications for chronic pain management

In an acute environment pain has potential protective benefits. However when pain becomes chronic this protective effect is lost and the pain becomes an encumbrance. Previously unheralded substances are being investigated in an attempt to alleviate …

Oxytocinergic regulation of endogenous as well as drug-induced mood

The interconnections between the serotonin and oxytocin pathways in the brain suggest that changes in oxytocin levels - arising from natural or drug-induced stimuli - lead to measureable changes in mood. In this paper, we review our findings in the …