pain

Resilience in the Face of Pain: A Chat With Liesbet Goubert

Interview for **Pain Research Forum**

Heart rate variability is associated with thermal heat pain threshold in males, but not females

Previous research has suggested that heart rate variability (HRV; the variability in the interval between successive heartbeats) can predict the perception of experimentally-induced pain (i.e., pain sensitivity). However, little research has sought …

Heart rate variability and sensitivity to experimentally induced pain: A replication

The neural systems involved in autonomic control and perception of pain are closely coupled, and extensive interactions between these sets of neural structures can be observed. The functional interaction of these systems is an important component of …

Sex and Gender Differences in Pain: A Chat With Edmund Keogh

Interview for **Pain Research Forum**

Parasympathomimetic effects of propranolol increases heart rate variability but does not influence experimental pain sensitivity or conditioned pain modulation in males - a randomised placebo-controlled crossover study

The autonomic nervous system (ANS) is capable of modulating pain. Aberrations in heart rate variability (HRV), reflective of ANS activity, are associated with experimental pain sensitivity, chronic pain, and more recently, pain modulatory mechanisms …

Intranasal oxytocin reduces heart rate variability during a mental arithmetic task: A randomised, double-blind, placebo-controlled cross-over study

Heart rate variability (HRV) refers to variation in the interval between successive heart beats. Low HRV is an indicator of potential autonomic nervous system dysfunction. People with chronic pain often display autonomic dysregulation, especially in …

Sex-specific effects of intranasal oxytocin on thermal pain perception: A randomised, double-blind, placebo-controlled cross-over study

Chronic neck and shoulder pain (CNSP) is a common musculoskeletal disorder in adults, which is linked to hypersensitivity to noxious stimuli. The hormone oxytocin has been implicated as a potential therapeutic for the management of chronic pain …

Catching Up With the 2017 North American Pain School Visiting Faculty: A Conversation with Jennifer Haythornthwaite

Interview for **Pain Research Forum**

Effects of explicit cueing and ambiguity on the anticipation and experience of a painful thermal stimulus

Many factors can influence the way in which we perceive painful events and noxious stimuli, but less is known about how pain perception is altered by explicit knowledge about the impending sensation. This study aimed to investigate the impact of …

Psychosocial factors and their influence on the experience of pain

Over the past 20 years, our understanding of social factors on pain experience has increased. Edwards et al. observed that the presence of a friend resulted in an increased pain threshold and tolerance to experimentally induced pain (cold pressor …